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Biomedical innovation is an intricate process that begins in the lab and spans years of effort to transform scientific discoveries into vaccines, diagnostics, devices, and therapies that improve patients’ lives. Over the past few decades, the United States has created and refined a remarkably productive framework for developing new biomedical innovations and bringing them to the marketplace—in fact, it’s one of the most dramatic success stories written by any American industry in the past century. Whether measured by international or domestic market share, revenue, jobs, number of regulatory approvals, patents, R&D expenditures, or publications in the biomedical field, the U.S. holds a commanding position.