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Following the sequencing of many genomes, genomics research has ed increasingly on elucidating the functions of gene products and their translation into the complex organisation of cells, tissues and organisms. These are the essential goals of functional genomics, the exploration of gene function on a global scale. Functional genomics investigations typically use large-scale assays in which many of the genes or proteins of an organism can be measured and tracked in parallel through space and time or under different environmental conditions. Revolutionary technologies, such as microarrays, are used, capable of high sample throughput and producing vast amounts of data requiring computational processing for interpretation. With the increasing assimilation of data by bioinformatics tools, integration into systems-level understanding has become a primary objective. Thus, functional genomics impacts in the most fundamental way on biological understanding, from individual molecules to cellular organisation and the physiology of whole organisms and their dysfunction in disease.....이하생략