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출처 : Furopean Science Foundation

Advancing Systems Biology for Medical Applications

Foreword

Systems biology is the systematic study of complex interactions in biological systems. It is a rapidly growing discipline that is playing an increasingly important role within the medical sciences. Among its anticipated benefits are contributions towards improving early diagnosis, designing patient-specific interventions, and accelerating the discovery of novel therapies for the benefit of European citizens. Several reports have recently provided science policy advice aimed at directing the advance of systems biology within Europe. Here, rather than revisiting the general recommendations given in such reports1,2, we provide a more specific, practical guide towards achieving major breakthroughs in biomedical systems biology, thereby covering issues that had not previously been addressed in sufficient detail. In particular, we identify and outline the necessary steps to promote the creation of pivotal biomedical systems biology tools and facilitating their translation into crucial therapeutic advances.

SysBioMed is a Specific Support Action (SSA) funded through the EC Framework Programme 6.  The core objective was to explore the potential of systems biology for medical research, therapy and drug development. To produce this Science Policy Briefing on systems biology, SysBioMed took a novel approach, bringing together recognised group leaders and young researchers to identify and prioritise suitable application areas for systems biology within the medical sciences. The challenges, hurdles and opportunities for systems biology in medical applications were discussed in 10 thematic workshops. This Policy Briefing selects and summarises some of the conclusions and recommendations generated during the workshops and discussions among the authors of this report......계속

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