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2009 Progress Report on Alzheimer's Disease:

 Translating New Knowledge

NIA is the lead Federal agency sponsoring and conducting research on many aspects of Alzheimer’s disease. The online annual report presents current research findings and summarizes recently completed and ongoing clinical trials and studies.

Introduction

A lzheimer’s disease (AD) is an age-related brain disorder that develops over many years. Its symptoms typically first appear after age 60. The course of AD varies from person to person, but in most people, the first symptom is memory loss. Memor decline becomes more serious as the disease progresses, and people often begin having problems with other cognitive functions, such as decision making (including financial) and language skills. People with Alzheimer’s may also experience behavior and personality s. Eventually, the loss of mental function becomes so severe that it impairs daily living and the ability to recognize family and friends. These losses are related to the breakdown of the connections between different classes of neurons (nerve cells) in the brain and the associated death of many of these cells.

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