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 New analyses of a large, nationwide study of antidepressant treatment have identified genetic variations linked to a controversial and concerning side effect: suicidal thinking. If confirmed, these variations could eventually provide the basis for a genetic test to predict who is most susceptible.

“We really want to be able to pick up the potential for worrisome side effects before we treatment,” says Francis McMahon, a psychiatric geneticist at the National Institute of Mental Health (NIMH), in Bethesda, MD, who led one of the studies.

 

 

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