바이오인

 

 

 

March 1-6, 2009
Four Points Sheraton / Holiday Inn Express
Ventura, CA

Chairs:
Richard L. Gallo & Paul McCray, Jr.

Vice Chairs:
Jens-M Schroder & Birgitta Agerberth

 

Application Deadline: Applications for this meeting must be submitted by February 8, 2009.

Please apply early, as some conferences become oversubscribed (full) before this deadline. If the conference is oversubscribed, it will be stated here. You will still be able to submit your application. However, it will only be considered by the Conference Chair if there are cancellations, making more seats available

 

 

The 2009 Gordon Conference on Antimicrobial Peptides will present the latest research on the biology and activities of antimicrobial peptides, essential and multifunctional host defense molecules employed by all organisms for innate defense. The Conference will feature a wide range of topics, such as structure/function analysis, regulation of expression, mechanisms of action, microbial avoidance strategies, human disease associations and model systems, and development of antimicrobial peptides as therapeutics. Invited speakers represent a diverse variety of scientific disciplines, including biochemistry, molecular genetics, microbiology, animal and plant biology, structural biology, medicine, innate immunity, signaling, and drug development. The Conference will bring together a collection of investigators who are at the forefront of their field, and will provide opportunities for junior scientists and graduate students to present their work in poster format and exchange ideas with leaders in the field. Some abstracts and poster presenters will be selected for short talks. The collegial atmosphere of this Conference, with programmed discussion sessions as well as opportunities for informal gatherings in the afternoons and evenings, provides an avenue for scientists from different disciplines to brainstorm and promotes cross-disciplinary collaborations in the various research areas represented.

 

 

SUNDAY
4:00 pm - 8:00 pm Arrival and Check-in
6:00 pm    Dinner
7:30 pm - 7:45 pm Welcome / Introductory Comments by GRC Site Staff
7:45 pm - 9:30 pm  Keynote Speakers: AMPs: Where we have we been and where are we going?
 Discussion Leaders: Richard Gallo (UCSD) and Paul McCray (U. Iowa)
7:45 pm - 8:25 pm Michael Karin (UCSD)
"Cell Signaling Networks in Innate Immunity"
8:25 pm - 8:35 pm  Discussion
8:35 pm - 9:15 pm Charles Bevins (UC Davis)
"History and Current Concepts of AMPs in Mucosal Defense"
9:15 pm - 9:25 pm  Discussion

 

MONDAY
7:30 am - 8:30 am Breakfast
8:30 am Group Photo
9:00 am - 12:30 pm  Peptides and other molecules as native antibiotics
 Discussion Leaders: Tomas Ganz (UCLA) and Nita Salzman (Medical College of Wisconsin)
9:00 am - 9:20 am Louisa P. Wu (U Maryland)
"Drosophila Innate Immunity"
9:20 am - 9:30 am  Discussion
9:30 am - 9:50 am Eddy Rubin (UC Berkeley)
"Genomic discovery tools for antimicrobials"
9:50 am - 10:00 am  Discussion
10:00 am Coffee Break
10:30 am - 10:50 am William Fenical (Scripps Institute of Oceanography)
"Antimicrobials from the sea, diversity and opportunity"
10:50 am - 11:00 am  Discussion
11:00 am - 11:20 am Anne E. Osbourn (UK Sainbury Lab)
"Innate Immunity in Plants"
11:20 am - 11:30 am  Discussion
11:30 am - 11:40 am  Talk selected from abstracts: TBA
11:40 am - 11:45 am  Discussion
11:45 am - 11:55 am  Talk selected from abstracts: TBA
11:55 am - 12:00 pm  Discussion
12:00 pm - 12:30 pm  General Discussion
12:30 pm Lunch
1:30 pm - 4:00 pm Free Time
4:00 pm - 6:00 pm Poster Session
6:00 pm Dinner
7:30 pm - 9:30 pm  Molecular models to understand AMP Function
 Discussion Leaders: Mei Hong (Iowa State University) and Hans-Georg Sahl (University of Bonn)
7:30 pm - 7:50 pm Judy Kim (UCSD)
"Understanding AMP-membrane interactions by optical spectroscopy"
7:50 pm - 8:00 pm  Discussion
8:00 pm - 8:20 pm Gerard Wong (U of Illinois)
"AMP interactions with membranes"
8:20 pm - 8:30 pm  Discussion
8:30 pm - 8:50 pm Ka Yee Lee (Univ of Chicago)
"X-ray and neutron scattering based approaches to AMP interactions wtih membranes"
8:50 pm - 9:00 pm  Discussion
9:00 pm - 9:30 pm  General Discussion

 

TUESDAY
7:30 am - 8:30 am Breakfast
9:00 am - 12:30 pm  Regulation of AMP expression
 Discussion Leaders: Gudmundur Gudmundsson (University of Iceland) and Ylva Engstrom (Stockholm University)
9:00 am - 9:20 am Jay Kolls (U Pitt)
"IL-17, IL-22 regulation of host defense programs"
9:20 am - 9:30 am  Discussion
9:30 am - 9:50 am Fritz Gombart (UCLA)
"Vitamin D and the antimicrobial response"
9:50 am - 10:00 am  Discussion
10:00 am Coffee Break
10:30 am - 10:50 am Jean-Marc Reichhart (ULP - IUF)
"Antimicrobial Defense in Drosophila: A Paradigm for Innate Immunity"
10:50 am - 11:00 am  Discussion
11:00 am - 11:20 am Adrian Martineau (Imperial College London)
"Induction of AMPs for the Treatment of mycobacterial disease"
11:20 am - 11:30 am  Discussion
11:30 am - 11:40 am  Talk selected from abstracts: TBA
11:40 am - 11:45 am  Discussion
11:45 am - 11:55 am  Talk selected from abstracts: TBA
11:55 am - 12:00 pm  Discussion
12:00 pm - 12:30 pm  General Discussion
12:30 pm Lunch
1:30 pm - 4:00 pm Free Time
4:00 pm - 6:00 pm Poster Session
6:00 pm Dinner
7:30 pm - 9:30 pm  Microbial Response to AMPs "tricks of the trade"
 Discussion Leaders: Andreas Peschel (University of Tubingen) and Victor Nizet (University of California)
7:30 pm - 7:50 pm Michael Apicella (Univ of Iowa)
"How Bacteria Hide from the Host"
7:50 pm - 8:00 pm  Discussion
8:00 pm - 8:20 pm Heidi Goodrich-Blair (Univ of Wisconsin)
"Mutualistic and pathogenic relationships between Microbes and their Hosts"
8:20 pm - 8:30 pm  Discussion
8:30 pm - 8:50 pm Pradeep Singh (Univ of Washington)
"Strategies of Pseudomonas for Evasion of Host Defense"
8:50 pm - 9:00 pm  Discussion
9:00 pm - 9:30 pm  General Discussion

 

WEDNESDAY
7:30 am - 8:30 am Breakfast
9:00 am - 12:30 pm  Cell and tissue specific roles for AMPs
 Discussion Leaders: Gill Diamond (UMDNJ) and Andy Ouellette (University of California, Irvine)
9:00 am - 9:20 am Allison McDermott (Univ of Houston)
"Functions of AMPs in eye disease"
9:20 am - 9:30 am  Discussion
9:30 am - 9:50 am Peter Elias (UCSF)
"Stress and the AMP Barrier of the skin"
9:50 am - 10:00 am  Discussion
10:00 am Coffee Break
10:30 am - 10:50 am Mike Welsh (Univ of Iowa)
"A porcine model of Cystic Fibrosis"
10:50 am - 11:00 am  Discussion
11:00 am - 11:20 am Lauren Bakaletz (Ohio State Univ)
"Middle Ear Host Defense and Otitis Media"
11:20 am - 11:30 am  Discussion
11:30 am - 11:40 am  Talk selected from abstracts: TBA
11:40 am - 11:45 am  Discussion
11:45 am - 11:55 am  Talk selected from abstracts: TBA
11:55 am - 12:00 pm  Discussion
12:00 pm - 12:30 pm  General Discussion
12:30 pm Lunch
1:30 pm - 4:00 pm Free Time
4:00 pm - 6:00 pm Poster Session
6:00 pm Dinner
7:00 pm - 7:30 pm Business Meeting
 (Nominations for the next Vice Chair; Fill out Conference Evaluation Forms; Discuss future Site & Scheduling preferences; Election of the next Vice Chair)
7:30 pm - 9:30 pm  Non-antimicrobial functions of the AMPs
 Discussion Leaders: Bob Hancock (University of British Columbia) and Mona Stahle (Karolinska Institutet)
7:30 pm - 7:50 pm Joost Oppenheim (NIH)
"How AMPs act as Alarmins"
7:50 pm - 8:00 pm  Discussion
8:00 pm - 8:20 pm Micheal Gilliet (UT-Houston)
"Control of Inflammation by LL37"
8:20 pm - 8:30 pm  Discussion
8:30 pm - 8:50 pm Peter Hiemstra (Netherlands)
"Function of AMPs in Lung Disease"
8:50 pm - 9:00 pm  Discussion
9:00 pm - 9:30 pm  General Discussion

 

THURSDAY
7:30 am - 8:30 am Breakfast
9:00 am - 11:30 am  Understanding biology through the AMPs
 Discussion Leaders: Birgitta Agerberth (Karolinska Institutet) and Jens Schroder (University of Kiel)
9:00 am - 9:20 am Lora Hooper (UT Southwestern)
"Microbial regulation of gut AMPs"
9:20 am - 9:30 am  Discussion
9:30 am - 9:50 am Speaker TBA
9:50 am - 10:00 am  Discussion
10:00 am Coffee Break
10:30 am - 10:50 am Ed Hollox (University of Leicester)
"Defensin gene copy number polymorphism and disease"
10:50 am - 11:00 am  Discussion
11:00 am - 11:20 am Greg Barsh (Stanford Univ)
"Defensin genes and mammalian color variation"
11:20 am - 11:30 am  Discussion
11:30 am - 12:30 pm  Hot Corner and late breaking news
 Presenters for short talks and discussion will be selected at the meeting by the Chairs and Vice-Chairs
12:30 pm Lunch
1:30 pm - 4:00 pm Free Time
4:00 pm - 6:00 pm Poster Session
6:00 pm Dinner
7:30 pm - 9:30 pm  Strategies and roadblocks to therapeutic applications
 Discussion Leaders: Mike Selsted (University of California, Irvine) and Jerry Weiss (University of Iowa)
7:30 pm - 7:50 pm Mike Zasloff (Georgetown)
"Understanding the Therapeutic Potential of AMPs"
7:50 pm - 8:00 pm  Discussion
8:00 pm - 8:20 pm Anton Stuetz (Novartis)
"Successful Drug Development in Pharma- Overcoming barriers"
8:20 pm - 8:30 pm  Discussion
8:30 pm - 8:50 pm Amram Mor (Technion)
"Potent Antimicrobial Peptide Mimetics from Oligoacyllysines (OAKs)"
8:50 pm - 9:00 pm  Discussion

 

FRIDAY
7:30 am - 8:30 am Breakfast
9:00 am Departure