행사/교육
The Biology of RNA Silencing (D6)
- 등록일2009-01-13
- 조회수2322
- 구분 국외
- 행사교육분류 행사
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주관기관
Witold Filipowicz and Erik Sontheimer
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행사장소
Victoria, British Columbia
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행사기간
2009-04-25 ~ 2009-04-30
- 원문링크
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첨부파일
The Biology of RNA Silencing (D6)
Meeting Summary
During the past decade, a set of pathways collectively known as “RNA silencing” has been shown to use small RNA molecules to regulate gene expression and protect cells from pathogens. RNA silencing pathways control an ever-expanding range of biological phenomena, and defects in these pathways lead directly to disease. In addition, small RNAs hold great promise as therapeutic agents. The physiological mechanisms of RNA silencing are only partially understood. Furthermore, small RNAs are known to affect gene expression at many different levels, but the ways in which these different levels of silencing are integrated remain obscure. Our ability to harness RNA silencing for therapeutic purposes depends critically on our knowledge of the underlying biology. The goals of this meeting are to bring together leading researchers working on different branches of RNA silencing to share their findings and facilitate a deeper understanding of the breadth and complexity of small RNA-related phenomena.
Meeting Program
6:30 - 7:30 PM Refreshments Palm Court
7:30 - 9:30 PM Keynote Session Crystal Ballroom
Registered attendees for this meeting can view Abstracts for this session starting on 03/25/2009
and
* Erik Sontheimer, Northwestern University, USA
Welcoming Remarks
Andrew Fire, Stanford University, USA
David P. Bartel, Massachusetts Institute of Technology, USA
8:00 - 11:00 AM Mechanism of Small RNAs I Salon A
Registered attendees for this meeting can view Abstracts for this session starting on 03/25/2009
Biogenesis of miRNAs
Erik Sontheimer, Northwestern University, USA
Assembly of RISCs
Gunter Meister†, Max Planck Institute of Biochemistry, Germany
Talk Title to be Determined
Dinshaw J. Patel, Memorial Sloan-Kettering Cancer Center, USA
Structural Biology of Argonaute-mediated RNA Silencing
11:00 AM- 1:00 PM Poster Setup Salon B
11:00 AM- On Own for Lunch
1:00 - 10:00 PM Poster Viewing Salon B
4:30 - 5:00 PM Coffee Available Victoria Conference Center-Level 2
5:00 - 7:00 PM Chromatin Silencing and Modification Salon A
Registered attendees for this meeting can view Abstracts for this session starting on 03/25/2009
RNAi and Heterochromatin in S. pombe
Nicholas J. Proudfoot, University of Oxford, UK
Talk Title to be Determined
Steven E. Jacobsen, HHMI/University of California, Los Angeles, USA
DNA methylation on Arabidopsis
7:30 - 10:00 PM Poster Session 1 Salon B
Registered attendees for this meeting can view Abstracts for this session starting on 03/25/2009
7:00 - 8:00 AM Poster Setup Salon B
8:00 - 11:00 AM Mechanism of Small RNAs II Salon A
Registered attendees for this meeting can view Abstracts for this session starting on 03/25/2009
siRNA-directed Arrest of Transcription Elongation
Craig C. Mello, University of Massachusetts Medical School, USA
Complexity of RNA Silencing in C. elegans
David C. Baulcombe, University of Cambridge, UK
Imprinted expression of siRNA loci in Arabidopsis
Peter Sarnow, Stanford University School of Medicine, USA
Talk Title to be Determined
11:00 AM- 12:00 PM Lunch Salon B
12:00 - 2:30 PM Poster Session 2 Salon B
Registered attendees for this meeting can view Abstracts for this session starting on 03/25/2009
2:30 - 4:30 PM Workshop 1: Identification of New miRNA Targets Salon A
* Mihaela Zavolan, Biozentrum, University of Basel, Switzerland
Short Talks to be Chosen from Abstracts, , USA
5:00 - 7:00 PM Intersection of RNAi/miRNA Silencing with Other Cellular Pathways
RNAi and Pathogen Defense in Plants
Bryan R. Cullen, Duke University Medical Center, USA
Viruses, microRNAs and RNA Interference
Craig P. Hunter, Harvard University, USA
Intercellular RNA Transporters in Worms and Vertebrates
7:00 PM- On Own for Dinner
8:00 - 11:00 AM Regulation of Translation and Stability by miRNAs Salon A
Registered attendees for this meeting can view Abstracts for this session starting on 03/25/2009
Elisa Izaurralde, MPI for Developmental Biology, Germany
GW182 Proteins are Essential for miRNA-mediated Gene Silencing in Animal Cells
Witold Filipowicz, Friedrich Miescher Institute for Biomedical Research, Switzerland
Regulation of miRNA Repression
Nahum Sonenberg, McGill University, Canada
Dissection of the miRNA Repression Mechanism in vitro
Joan A. Steitz, Yale U/Howard Hughes Medical Institute, Yale University, USA
"MicroRNPs: Versatile Regulators of Translation in Vertebrate Cells"
11:00 AM- 1:00 PM Poster Setup Salon B
11:00 AM- On Own for Lunch
1:00 - 10:00 PM Poster Viewing Salon B
2:30 - 4:30 PM Workshop 2: Lessons from Deep Sequencing Salon A
Short Talks to be Chosen from Abstracts, , USA
5:00 - 7:00 PM RNA Silencing in the Germline Salon A
Registered attendees for this meeting can view Abstracts for this session starting on 03/25/2009
Gregory J. Hannon, Cold Spring Harbor Laboratory, USA
Talk Title to be Determined
Mikiko C. Siomi, Keio University School of Medicine, Japan
PiRNA Biogenesis Systems in Drosophila Germline Cells
Rene Ketting, Hubrecht Institute, Netherlands
RNAi and Chromosome Segregation
Short Talk to be Chosen from Abstracts,
7:30 - 10:00 PM Poster Session 3 Salon B
Registered attendees for this meeting can view Abstracts for this session starting on 03/25/2009
7:00 - 8:00 AM Breakfast Crystal Ballroom
8:00 - 11:00 AM MicroRNAs in Development Salon A
Registered attendees for this meeting can view Abstracts for this session starting on 03/25/2009
Richard W. Carthew, Northwestern University, USA
miRNA Circuits
Victor Ambros, University of Massachusetts, USA
MicroRNA Pathways in Animal Development
Antonio J. Giraldez, Yale School of Medicine, USA
Function of miRNAs in Zebrafish Embryogenesis
Short Talk(s) to be Chosen from Abstracts,
11:00 AM- On Own for Lunch
4:30 - 5:00 PM Coffee Available Victoria Conference Center-Level 2
5:00 - 7:00 PM Small RNAs in Medicine Salon A
Registered attendees for this meeting can view Abstracts for this session starting on 03/25/2009
John Van der Oost, Wageningen University, Netherlands
Interference by small CRISPR RNA in prokaryotes
Gunther Hartmann, Universitätsklinikum Bonn, Germany
RIG-I immunorecognition of siRNA and application for tumor therapy
Beverly L. Davidson, University of Iowa, USA
RNA Silencing and Neurodegenerative Diseases
Short Talk to be Chosen from Abstracts,
8:00 - 11:00 PM Entertainment Crystal Ballroom
Departure
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