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행사/교육

Complex Lipids in Biology: Signaling, Compartmentalization and Disease

  • 등록일2009-01-13
  • 조회수2180
  • 구분 국외
  • 행사교육분류 행사
  • 주관기관
    http://www.keystonesymposia.org/
  • 행사장소
    Keystone Symposia - Olympic Valley, CA
  • 행사기간
    2009-04-22 ~ 2009-04-27
  • 원문링크
  • 첨부파일

Complex Lipids in Biology: Signaling,

Compartmentalization and Disease

 
 
 
Meeting Summary

Complex lipids constitute a diverse family of biomolecules of seven general classes that serve essential roles in Biology. For example, lipids include structural phospholipids that form cellular membranes but are also the reservoirs and source of polyunsaturated fatty
acids that are signaling mediators. Intense research effort over the past years has substantially changed our understanding of lipid biochemistry and lipid function in cells with the application of new tools and techniques to study these molecules. This meeting will
bring together a group of individuals who have the common goal of understanding the role that lipids play in cell biology, physiology and disease processes.
 
 
Meeting Program
 
Wednesday, April 22
3:00 - 7:30 PM  Registration                                                                Lobby Alcove 
6:30 - 7:30 PM  Refreshments                                            Sierra Prefunction A,B,C,D 
7:30 - 8:30 PM  Keynote Address                                          Grand Sierra Ballroom 
Registered attendees for this meeting can view Abstracts for this session starting on 03/22/2009  
Takao Shimizu, University of Tokyo, Japan
Phospholipid Metabolism: Phospholipases and Acyltransferases  
 
Thursday, April 23
7:00 - 8:00 AM  Breakfast                                                                  Alpine Ballroom 
8:00 - 11:00 AM  Phosphoinositides and Signaling (Joint)
Registered attendees for this meeting can view Abstracts for this session starting on 03/22/2009            Grand Sierra Ballroom 
Lewis C. Cantley, Harvard Medical School, USA
Growth Control by the PI3K/mTOR Pathway  
Len R. Stephens, Babraham Institute, UK
The Role of PI3K's in the Regulation of the Neutrophil NADPH Oxidase   
Speaker to be Announced, 
Mark A. Lemmon, University of Pennsylvania School of Medicine, USA
PH Domains and Other Phosphoinositide & Phospholipid Binding Domains  
9:20 - 9:40 AM  Coffee Break                                                  Sierra Prefunction A,B,C,D 
11:00 AM- 1:00 PM  Poster Setup                                               Cascades / Restaurant 
11:00 AM-  On Own for Lunch  
1:00 - 10:00 PM  Poster Viewing                                                  Cascades / Restaurant 
4:30 - 5:00 PM  Coffee Available                                               Sierra Prefunction A,B,C,D 
5:00 - 7:00 PM  Phospholipases and Acyl Transferases
Registered attendees for this meeting can view Abstracts for this session starting on 03/22/2009                                                                                              Grand Sierra C,D 
Christina C. Leslie, National Jewish Medical and Research Center, USA
cPLA2 Isoforms: Biochemistry and Function  
Michael H. Gelb, University of Washington, USA
Role of Phospholipases A2 in Eicosanoid Generation  
Michael J.O. Wakelam, Babraham Institute, UK
Phospholipase D and Disease  

Following Session is for PI 3-Kinases (Z3)
5:00 - 7:00 PM
  PI3 Kinase Pathway and Inflammation                          Grand Sierra A,B 
Registered attendees for this meeting can view Abstracts for this session starting on 03/22/2009  
Phillip T. Hawkins, Babraham Institute, UK
PI3K Signaling in Neutrophils  
Matthias P. Wymann, University of Basel, Switzerland
PI3-Kinase Signaling in Immune Cells  
Speaker to be Announced, 
7:00 - 8:00 PM  Social Hour w/ Lite Bites                                      Cascades / Restaurant 
7:30 - 10:00 PM  Poster Session 1
Registered attendees for this meeting can view Abstracts for this session starting on 03/22/2009  Cascades / Restaurant 
 
Friday, April 24
7:00 - 8:00 AM  Breakfast                                                                         Alpine Ballroom 
8:00 - 11:00 AM  Leukotrienes: New Frontiers                                          Grand Sierra C,D 
Registered attendees for this meeting can view Abstracts for this session starting on 03/22/2009   
Jilly F. Evans, Amira Pharmaceuticals, USA
5-Lipoxygenase-Activating Protein (FLAP) as a Therapeutic Target  
Marc Peters-Golden, University of Michigan, USA
Why Do We Have a 5-Lipoxygenase Pathway? Leukotrienes in Innate Immune Cell Activation  
Robert C. Murphy, University of Colorado Denver, USA
Transcellular Biosynthesis of Leukotrienes  
Colin D. Funk, Queen's University, Canada
Novel Functions for Leukotrienes Based on Cysteinyl Leukotriene 2 Receptor Expression Patterns  
Following Session is for PI 3-Kinases (Z3)
8:00 - 11:00 AM
  PI 3-Kinase Signaling: Downstream Effectors
Registered attendees for this meeting can view Abstracts for this session starting on 03/22/2009  Grand Sierra A,B 
Bart Vanhaesebroeck, Barts & The London School of Medicine, UK
Roles of PI3 Kinase Isoforms   
Kevan M. Shokat, University of California, San Francisco, USA
Discovery of a New Class of mTOR Inhibitors Reveals Rapamycin Resistant Outputs of mTORC1 and mTORC2.  
Ana Clara Carrera, Centro Nacional Biotechnologia, Spain
Distinct activation requirements and function for Phosphoinositide 3-kinase p110alpha and beta in cell division  
Levi A. Garraway, Dana Farber Cancer Institute, USA
Talk Title to be Determined  
9:20 - 9:40 AM  Coffee Break                                                     Sierra Prefunction A,B,C,D 
11:00 AM- 1:00 PM  Poster Setup                                              Cascades / Restaurant 
11:00 AM-  On Own for Lunch  
1:00 - 10:00 PM  Poster Viewing                                                 Cascades / Restaurant 
4:30 - 5:00 PM  Coffee Available                                               Sierra Prefunction A,B,C,D 
5:00 - 7:00 PM  Sphingolipid Signaling                                       Grand Sierra C,D 
Registered attendees for this meeting can view Abstracts for this session starting on 03/22/2009  
Timothy T. Hla, University of Connecticut, USA
S1P Signaling in the Vasculature  
Shaun R. Coughlin, University of California, San Francisco, USA
Compartmentalization of S1P Signaling  
Richard L. Proia, National Institutes of Health, USA
Sphingosine-1-Phosphate and its Role in Physiology  

Following Session is for PI 3-Kinases (Z3)
5:00 - 7:00 PM
  Cell Growth, Metabolism and Aging                        Grand Sierra A,B 
Registered attendees for this meeting can view Abstracts for this session starting on 03/22/2009  
David M. Sabatini, Whitehead Institute for Biomedical Research, USA
Crosstalk between PI3K and mTOR   
Speaker to be Announced, 
Anne Brunet,
Stanford University, USA
Role of FOXO Transcription Factors in Aging  
7:00 - 8:00 PM  Social Hour w/ Lite Bites                                Cascades / Restaurant 
7:30 - 10:00 PM  Poster Session 2                                          Cascades / Restaurant 
Registered attendees for this meeting can view Abstracts for this session starting on 03/22/2009 
 
 
Saturday, April 25
7:00 - 8:00 AM
  Breakfast                                                                    Alpine Ballroom 
8:00 - 11:00 AM  Ceramides, LysoPA and Other Lipid Mediators
Registered attendees for this meeting can view Abstracts for this session starting on 03/22/2009  Grand Sierra C,D 
 Jerold J. Chun, The Scripps Research Institute, USA
Lysophospholipid Receptors: Signaling and Disease-Modifying Mechanisms  
 Sarah Spiegel, Virginia Commonwealth University School of Medicine, USA
Signaling and Compartmentalization of Sphingosine-1-Phosphate  
 Teresa M. Dunn, Uniformed Services University of the Health Sciences, USA
Serine Palmitoyltransferases - A Family of Heterotrimeric Isozymes?  
 Benjamin F. Cravatt III, The Scripps Research Institute, USA
Multidimensional Profiling and Lipid Ether Signaling  

Following Session is for PI 3-Kinases (Z3)
8:00 - 11:00 AM
  PI 3-Kinase Signaling and Cancer                Grand Sierra A,B 
Registered attendees for this meeting can view Abstracts for this session starting on 03/22/2009  
Pier Paolo Pandolfi, Harvard Medical School/BIDMC, USA
PTEN and the Control of Tumorigenesis  
Tak W. Mak, Campbell Family Institute for Breast Cancer Research at PMH, UHN, Canada
PI 3-Kinase Signaling and Tumorigenesis  
Jean Zhao, Dana-Farber Cancer Institute, USA
Class IA PI3K Isoforms in Signaling and Cancer  
Jeffrey Adam Engelman, Massachusetts General Hospital, USA
Talk Title to be Determined  
9:20 - 9:40 AM  Coffee Break                                                  Sierra Prefunction A,B,C,D 
11:00 AM- 1:00 PM  Poster Setup                                          Cascades / Restaurant 
11:00 AM-  On Own for Lunch  
1:00 - 10:00 PM  Poster Viewing                                             Cascades / Restaurant 
4:30 - 5:00 PM  Coffee Available                                            Sierra Prefunction A,B,C,D 
5:00 - 7:00 PM  Recent Advances in PGH Synthate and 5-lipoxygenase
Registered attendees for this meeting can view Abstracts for this session starting on 03/22/2009  Grand Sierra C,D 
 William L. Smith, University of Michigan, USA
Cyclooxygenase Homodimers Function as Conformational Heterodimers with Allosteric and Catalytic Subunits  
 Garret A. FitzGerald, University of Pennsylvania, USA
Translational Therapeutics of the Arachidonic Acid Cascade  
 Frank A. Fitzpatrick, University of Utah, USA
Akt Activation by Arachidonic Acid Metabolism  

Following Session is for PI 3-Kinases (Z3)
5:00 - 7:00 PM
  Phosphatases and Control of the PI 3-Kinase Pathway
Registered attendees for this meeting can view Abstracts for this session starting on 03/22/2009  Grand Sierra A,B 
Alexandra C. Newton, University of California, San Diego, USA
Signal Termination: PHLiPPing the Switch in Cell Signaling   
Nick Reid Leslie, University of Dundee, UK
The Regulation and Mechanisms of Action of PTEN  
Takehiko Sasaki, Akita University School of Medicine, Japan
In vivo Roles of Phosphoinositide Phosphatases  
7:00 - 8:00 PM  Social Hour w/ Lite Bites                              Cascades / Restaurant 
7:30 - 10:00 PM  Poster Session 3                                       Cascades / Restaurant 
Registered attendees for this meeting can view Abstracts for this session starting on 03/22/2009 
 
Sunday, April 26
7:00 - 8:00 AM  Breakfast                                                                     Alpine Ballroom 
8:00 - 11:00 AM  Phospholipases, Kinases and Signaling Systems
Registered attendees for this meeting can view Abstracts for this session starting on 03/22/2009  Grand Sierra C,D 
Michael A. Frohman, Stony Brook University, USA
Regulation of Exocytosis, Cell Shape and Movement, and Mitochondrial Fusion by Lipid Signaling Pathways  
H. Alex Brown, Vanderbilt University, USA
Signaling Lipid Analysis and Phospholiase D  
Ana Olivera, NIAMS, National Institutes of Health, USA
Sphingosine-1-phosphate, a determinant of mast cell responsiveness  
Julie D. Saba, Children’s Hospital Oakland Research Institute, USA
S1P Lyase in Development and Disease: Sphingolipid Metabolism Takes Flight  

Following Session is for PI 3-Kinases (Z3)
8:00 - 11:00 AM
  PI 3-Kinase Pathway Modulation: Transition to the Clinic I
Registered attendees for this meeting can view Abstracts for this session starting on 03/22/2009  Grand Sierra A,B 
Neal Rosen, Memorial Sloan-Kettering Cancer Center, USA
Integration of PI3K and ERK Signaling--Therapeutic Implications   
Richard F. Wooster, GlaxoSmithKline, USA
Talk Title to be Determined   
Christian Rommel, Intellikine, USA
Talk Title to be Determined  
 Speaker to be Announced, 
9:20 - 9:40 AM  Coffee Break                                           Sierra Prefunction A,B,C,D 
11:00 AM-  On Own for Lunch  
4:30 - 5:00 PM  Coffee Available                                       Sierra Prefunction A,B,C,D 
5:00 - 7:00 PM  Polyunsaturated Fatty Acids and Lipid Peroxidation
Registered attendees for this meeting can view Abstracts for this session starting on 03/22/2009  Grand Sierra C,D  
Lawrence J. Marnett, Vanderbilt University School of Medicine, USA
Novel Strategies to Identify Lipid-Protein Covalent Adducts  
Suzanne E. Barbour, Virginia Commonwealth University, USA
Lipoprotein-Associated PLAA2/ PAF-AH: An Important Enzyme in Metabolic Diseases  
Speaker to be Announced, 
Following Session is for PI 3-Kinases (Z3)
5:00 - 7:00 PM
  PI 3-Kinase Pathway Modulation: Transition to the Clinic II
Registered attendees for this meeting can view Abstracts for this session starting on 03/22/2009  Grand Sierra A,B 
Paul Workman, Institute of Cancer Research, UK
Drugging the PI3 Kinome for Cancer Treatment   
S
peakers to be Announced, 
7:00 - 8:00 PM  Social Hour w/ Lite Bites                                  Cascades / Restaurant 
8:00 - 11:00 PM  Entertainment                                                 Cascades / Restaurant 
 
 
Monday, April 27
 Departure 

 
Abstract Deadlines and Pricing

- On and before December 23, 2008, the cost is $50.00, which is deducted from your registration fee when you register for this meeting.
- After December 23, 2008, there is an additional $50.00 fee, which is NOT deducted from the registration fee.
- You may submit your abstract on this web site until January 26, 2009.
(After this date you will need to contact our office about submitting an abstract.)
- Submitting an abstract does not constitute or guarantee registration.
 
Registration Deadlines and Pricing
- You may register for this meeting on this web site until April 22, 2009.
- The Registration Fee includes the Abstract Submission Fee.
For more information and other registration options, see How to Register.
 
Non-student Fees
- The Registration Fee is $645.00 on and before February 23, 2009.
- After February 23, 2009, the Registration Fee is $745.00
 
Student Fees
- To qualify for the Student Discount, you must complete the Student Verification section of the Registration Form.
- The Student Registration Fee is $420.00 on and before February 23, 2009.
- After February 23, 2009, the Registration Fee is $520.00
What is included in the registration fee?
- Admission to plenary speaker talks and poster displays
- Abstract book
- Breakfast service and coffee breaks
- Refreshments at poster sessions
 
Registration fee generally does NOT include:
- Lodging
- Transportation
- Lunches (some locations will provide lunch instead of evening social hour food...check program for specifics)
- Dinners