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Protein Dynamics, Allostery and Function

 

 

With recent progress in exploring biomolecular systems dynamics, an emerging view is that of the ‘intrinsic ability’ of biomolecular systems to populate an ensemble of fluctuating conformations, or alternative states, which include, in particular, the functional forms stabilized upon ligand/substrate binding or protein-protein interactions. Allosteric changes in conformations, or signal transduction mechanisms, thus emerge as properties encoded by the structure and energy landscape, which are evolutionarily selected due to their functional predisposition. Of particular interest is to elucidate the mechanisms of information flow, not only at the level of residue interactions, but also between the components of biomolecular machines or cell signaling networks. This Keystone Symposia meeting will provide a forum for researchers from diverse fields to explore the basic principles underlying allosteric responses at the molecular level, and their higher (cellular) level consequences, and to exchange expertise on methods to illuminate key dynamic properties of biomolecular systems.

 

 

 

Friday, June 5
3:00 - 7:30 PM  Registration                                                                 Longs Peak Foyer 
6:30 - 7:30 PM  Refreshments                                                              Longs Peak Foyer 
7:30 - 8:30 PM  Keynote Address
Registered attendees for this meeting can view Abstracts for this session starting on 05/05/2009  Grays/Long Peak 

 

Saturday, June 6
7:00 - 8:00 AM  Breakfast                                                                        Quandary Peak 
8:00 - 11:00 AM  Dynamics, Energy Landscapes and Evolutionary Selection
Registered attendees for this meeting can view Abstracts for this session starting on 05/05/2009  Grays/Long Peak 
9:20 - 9:40 AM  Coffee Break                                                               Longs Peak Foyer 
11:00 AM- 1:00 PM  Poster Setup                                                           Quandary Peak 
11:00 AM-  On Own for Lunch  
1:00 - 10:00 PM  Poster Viewing                                                             Quandary Peak 
2:30 - 4:30 PM  Workshop                                                                      Grays/Long Peak  
Short Talks to be Chosen from Abstracts, , USA 
4:30 - 5:00 PM  Coffee Available                                                             Longs Peak Foyer 
5:00 - 7:00 PM  Catalysis and Allostery
Registered attendees for this meeting can view Abstracts for this session starting on 05/05/2009  Grays/Long Peak 

7:00 - 8:00 PM  Social Hour w/ Lite Bites                                                 Quandary Peak 
7:30 - 10:00 PM  Poster Session 1
Registered attendees for this meeting can view Abstracts for this session starting on 05/05/2009  Quandary Peak 

 

Sunday, June 7
7:00 - 8:00 AM  Breakfast                                                                       Quandary Peak 
8:00 - 11:00 AM  Allosteric Events in Membrane Proteins
Registered attendees for this meeting can view Abstracts for this session starting on 05/05/2009  Grays/Long Peak 
9:20 - 9:40 AM  Coffee Break                                                              Longs Peak Foyer 
11:00 AM- 1:00 PM  Poster Setup                                                          Quandary Peak 
11:00 AM-  On Own for Lunch  
1:00 - 10:00 PM  Poster Viewing                                                             Quandary Peak 
4:30 - 5:00 PM  Coffee Available                                                          Longs Peak Foyer 
5:00 - 7:00 PM  Dynamics and Biomolecular Machines
Registered attendees for this meeting can view Abstracts for this session starting on 05/05/2009  Grays/Long Peak 
7:00 - 8:00 PM  Social Hour w/ Lite Bites                                              Quandary Peak 
7:30 - 10:00 PM  Poster Session 2
Registered attendees for this meeting can view Abstracts for this session starting on 05/05/2009  Quandary Peak 

 

Monday, June 8
7:00 - 8:00 AM  Breakfast                                                                       Quandary Peak 
8:00 - 11:00 AM  Signal Propagation in Molecular and Cellular Systems I
Registered attendees for this meeting can view Abstracts for this session starting on 05/05/2009  Grays/Long Peak 

9:20 - 9:40 AM  Coffee Break                                                             Longs Peak Foyer 
11:00 AM- 1:00 PM  Poster Setup                                                         Quandary Peak 
11:00 AM-  On Own for Lunch  
1:00 - 10:00 PM  Poster Viewing                                                             Quandary Peak 
4:30 - 5:00 PM  Coffee Available                                                          Longs Peak Foyer 
5:00 - 7:00 PM  Signal Propagation in Molecular and Cellular Systems II
Registered attendees for this meeting can view Abstracts for this session starting on 05/05/2009  Grays/Long Peak 

7:00 - 8:00 PM  Social Hour w/ Lite Bites                                               Quandary Peak 
7:30 - 10:00 PM  Poster Session 3
Registered attendees for this meeting can view Abstracts for this session starting on 05/05/2009  Quandary Peak 

 

Tuesday, June 9
7:00 - 8:00 AM  Breakfast                                                                      Quandary Peak 
8:00 - 11:00 AM  Novel Methods for Dynamics and Allostery
Registered attendees for this meeting can view Abstracts for this session starting on 05/05/2009  Grays/Long Peak 

9:20 - 9:40 AM  Coffee Break                                                              Longs Peak Foyer 
11:00 AM-  On Own for Lunch  
4:30 - 5:00 PM  Coffee Available                                                         Longs Peak Foyer 
5:00 - 7:00 PM  Novel Methods for Equilibrium Fluctuations
Registered attendees for this meeting can view Abstracts for this session starting on 05/05/2009  Grays/Long Peak 
7:00 - 8:00 PM  Social Hour w/ Lite Bites                                             Quandary Peak 
8:00 - 11:00 PM  Entertainment                                                             Quandry Peak 

 

 

Wednesday, June 10
 Departure 

 

- You may register for this meeting on this web site until June 5, 2009.
- The Registration Fee includes the Abstract Submission Fee.
- For more information and other registration options, see How to Register.

Non-Student Fees
- The Registration Fee is $645.00 on and before April 6, 2009.
- After April 6, 2009, the Registration Fee is $745.00

Student Fees
- To qualify for the Student Discount, you must complete the Student Verification section of the Registration Form.
- The Student Registration Fee is $420.00 on and before April 6, 2009.
- After April 6, 2009, the Registration Fee is $520.00