정책동향
Gene-Environment Interaction in Chronic Disease
- 등록일2011-12-02
- 조회수4736
- 분류정책동향 > 기타 > 기타
-
자료발간일
2011-11-02
-
출처
European Science Foundation
-
원문링크
-
키워드
#Gene-Environment
- 첨부파일
Gene-Environment_Interaction_in_Chronic_Disease.PDF
Gene-Environment Interaction in Chronic Disease
Executive Summary
Changed lifestyle conditions such as improved nutrition and exercise status have contributed to a significantly increased longevity in Western Europe. However, evidence indicates that changes in living conditions also play an important role with respect to the alarming increased incidence rates that have been observed for chronic diseases.
The complex interplay between genes and environment in chronic inflammatory and immune-
mediated diseases is generally not well understood. Based on genetic predisposition, environmental factors largely determine phenotype development. In this context, the complex gut-associated micro-bial ecosystem (gut-microbiota) for example and nutrition-related factors are known to be important environmental triggers for the development and modification of lifestyle-related chronic diseases and metabolic pathologies, and the hygiene hypoth-esis provides a further challenging concept for the explanation of increases in chronic inflammatory diseases.
....(계속)
☞ 자세한 내용은 첨부파일을 참고하시기 바랍니다.