연구 보고서
인플루엔자연구_기술122권.pdf
개요
1. 인플루엔자 연구개요
인플루엔자 바이러스는 숙주에게 감염성의 급성 열성 호흡기 질환을 발병시키고, 유행시 그 전염성이 강하여 그 전파가 국경을 쉽게 넘을 수 있으며, 예측하기 어려운 방향으로 다양하게 변이되어 이종간의 감염을 나타날 수 있어, 전 세계적인 공동 대응책 마련과 감시체계의 필요성이 증대되고 있음
가. 인플루엔자란?
1) 인플루엔자의 정의 및 특징
인플루엔자(Influenza, 독감)는 인플루엔자바이러스에 의해서 발병되는 급성 감염상 질환으로, 높은 전염성을 가지며 매년 세계적 규모의 유행을 일으킴
○ 대표적인 증상은 고열과 두통, 근육통이며, 인후의 염증, 통증, 기침 등의 호흡기 증상을 수반함
○ 인플루엔자 바이러스에 감염 시, 건강한 사람은 가벼운 증상만 보이고 회복될 수 있으나, 노약자, 만성질환 보유자, 그리고 타 질환을 겪고 있는 환자는 심할 경우 합병증에 의한 사망에 이를 수도 있음
인플루엔자는 바이러스의 유전자 변이(항원변이)의 정도에 따라 계절형 유행과 대유행으로 나뉨
○ 계절형 유행(epidemic)은 항원소변이(antigenic drift)에 의한 것이며, 주로 겨울철에 유행......계속
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목차
1. 인플루엔자 연구개요
가. 인플루엔자란? ······························································································· 1
1) 인플루엔자의 정의 및 특징 ······································································ 1
2) 인플루엔자 연구영역 및 기술분류 ·····························································3
나. 인플루엔자 연구의 필요성 ·········································································· 4
2. 서지분석
가. 특허분석 ········································································································· 6
1) 해외특허로 살펴본 인플루엔자 분야 세계동향 ······································ 7
2) 해외에 출원된 특허로 살펴본 인플루엔자 분야 국내동향 ················· 14
3) 한국 특허청에 출원된 특허로 살펴본 인플루엔자 분야 국내동향 ··· 17
나. 논문분석 ······································································································ 22
1) 논문으로 살펴본 인플루엔자 분야 세계동향 ······································· 23
2) 논문으로 살펴본 인플루엔자 분야 국내동향 ······································· 30
다. 관련 시장 및 산업동향 분석 ···································································· 34
1) 백신 개발 기술 분야 ··············································································· 34
2) 예방 및 치료제 개발 분야-항바이러스 제제를 중심으로 ················· 38
3. 기술개발동향
가. 백신 개발 기술 분야 연구 동향 ······························································· 40
1) 연구개발 동향(I)-인플루엔자 백신 개발의 당면과제 ··························40
2) 연구개발 동향(II)-주요 개발사들을 중심으로 ···································· 42
나. 예방 및 치료제 개발 분야-항바이러스 제제를 중심으로 ···················· 46
다. 인플루엔자 검사 및 진단 기술 동향-CDC 승인기술을 중심으로 ····· 49
4. 정책동향
가. 미국의 정책동향 ························································································· 51
나. 세계보건기구(WHO)의 인플루엔자 대유행 단계 구분 ························· 52
다. 국내 정책동향 ····························································································· 54
5. 시사점 및 대응방향
6. 참고문헌
지식