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BIOTECH TRENDS

Anticipation of new medical and technological innovations is critical to successful investment in biotechnology and pharmaceutical companies. This report identifies 9 trends as well as 4 technologies that we expect to capture investors’ attention in 2002 and beyond. Companies poised to take advantage of each trend are identified. Monoclonal antibodies are becoming successful therapeutics, and two of our trends relate to technological advances that will improve monoclonals. Three trends cover investment choices in specific therapeutic areas: neurodegenerative disease, cancer, and diabetes.

Three trends

- pharmacogenomics, genetic diagnostics, and target validation

- relate to applications stemming from knowledge of the human genome.

Finally, antisense as a new approach to drug development is profiled. In addition to these trends, four technologies-stem cells, gene therapy, proteomics, and DNA microarrays / bioinformatics-are discussed for their long term investment potential.

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